Matt Gibson: The blueprints of tissue architecture

Matt Gibson: The blueprints of tissue architecture

JCB • VOLUME 186 • NUMBER 2 • 2009 166 E pithelia come in all shapes and sizes. The cells themselves can be columnar, cuboidal, or squamous in shape, whereas the tissue as a whole can take up a variety of forms. Drosophila imaginal discs, for example, are fl attened epithelial sacs that develop into different adult organs and appendages, such as the eye and wing. Matt Gibson began his scientifi...

Enterprise Architecture – from Blueprints to Design Services

This paper looks at the evolution of Enterprise Architecture modeling and use, since its birth in the late 1970’s, then looks at the role of architectures in leading companies today, and finally developments to add more value to past investments are presented and discussed. Until recently enterprise architecture projects have been focused on business and systems information gathering and presen...

Architectural Blueprints—The “4+1” View Model of Software Architecture

This article presents a model for describing the architecture of software-intensive systems, based on the use of multiple, concurrent views. This use of multiple views allows to address separately the concerns of the various ‘stakeholders’ of the architecture: end-user, developers, systems engineers, project managers, etc., and to handle separately the functional and non functional requirements...

Towards blueprints for network architecture, biophysical dynamics and signal transduction.

We review mathematical aspects of biophysical dynamics, signal transduction and network architecture that have been used to uncover functionally significant relations between the dynamics of single neurons and the networks they compose. We focus on examples that combine insights from these three areas to expand our understanding of systems neuroscience. These range from single neuron coding to ...

Matt Blaze